Edaravone-Loaded Alginate-Based Nanocomposite Hydrogel Accelerated Chronic Wound Healing in Diabetic Mice
نویسندگان
چکیده
منابع مشابه
Edaravone, a free radical scavenger, accelerates wound healing in diabetic mice.
UNLABELLED Refractory wound healing is a major complication of diabetes, which restricts wound healing by interfering with the inflammatory response, decreasing granulation, causing peripheral neuropathy, and inhibiting angiogenesis. Oxidative stress has been proposed as an important pathogenic factor in diabetic wound complications. Edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one) is a strong f...
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OBJECTIVES/HYPOTHESIS The purpose of this study was to investigate the regenerative efficacy of an injectable hyaluronic acid/mildly cross-linked alginate hydrogel (HA/ALG hydrogel) containing human adipose-derived mesenchymal stem cells (hAdMSCs) for vocal fold (VF) wound healing. STUDY DESIGN Animal research. METHODS HA/ALG hydrogel containing hAdMSCs was injected into the VFs of rabbits ...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2019
ISSN: 1660-3397
DOI: 10.3390/md17050285